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Palisade Bio Doses First Patient In Its ASCENTRA-UC Phase 2b Clinical Trial Evaluating PALI-2108 In ~204 Patients With Moderately To Severely Active Ulcerative Colitis; 12-Week Topline Results Expected In Q4 2027

Oct 28, 2026 · 08:34 AM ET· updated 1h ago

PALI-2108 is an investigational, gut-activated, once-daily oral PDE4 inhibitor prodrug designed for sustained exposure and anti-inflammatory activity with the potential to improve tolerability29 of 30 planned U.S. sites

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Why It Matters

Palisade Bio started testing a new ulcerative colitis medicine on real patients. Watch for results in late 2027 to see if the treatment actually works.

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Source: Benzinga · Read the original report at the publisher. Headline and figures shown for context; data may be delayed.

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