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Alliance Foundation Trials And Natera Launch AFT-70 NAVIGATE, Randomized Phase III Trial Evaluating MRD-Guided Treatment Strategy For Patients With Intermediate And High-Risk ER-Positive/HER2-Negative Early Breast Cancer

Oct 5, 2026 · 08:04 AM ET· updated 1h ago

Trial will use Natera’s ultrasensitive MRD test, Signatera Genome with Phased and Structural Variants, paired with giredestrant monotherapy, Genentech’s investigational oral SERD, aiming to spare patients unnecessary

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Why It Matters

Natera is running a big cancer study with a partner company. The test helps doctors figure out which patients need extra treatment.

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Source: Benzinga · Read the original report at the publisher. Headline and figures shown for context; data may be delayed.

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