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Sionna Therapeutics To Advance SION-451/SION-2222 CF Combo Into Phase 2a; Cuts Workforce By 46% To Extend Cash Runway Into The Second Half Of 2029

Sep 14, 2026 · 04:03 PM ET· updated 53m ago

Post hoc analyses of SION-719 PreciSION CF subset showed a mean placebo-adjusted sweat chloride reduction of up to -8.6 mmol/L consistent with NBD1 biological activityDual combination Phase 2a trial expected to initiate

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Why It Matters

Sionna is testing a new cystic fibrosis medicine combo in the next phase. The company is cutting staff to save money and keep going longer.

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Source: Benzinga · Read the original report at the publisher. Headline and figures shown for context; data may be delayed.

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