Novartis’ Pelacarsen Phase III Lp(a)HORIZON Trial Fails Primary Cardiovascular Endpoint; Lowered Lp(a) Levels But Did Not Reduce CV Events
Novartis today announced that the pelacarsen phase III Lp(a)HORIZON trial, a pioneering cardiovascular outcomes study, did not meet its primary endpoint of reducing the risk of cardiovascular events, a composite of
Novartis tested a new medicine to prevent heart problems by lowering a blood substance, but it worked on the substance without preventing enough heart events. When a medicine doesn't work as hoped, investors watch to see if the company has other plans.
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