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Novo Nordisk Announces Ziltivekimab Did Not Translate Into Major Adverse Cardiovascular Events Risk Reduction During Phase 3 Trial In Patients With Atherosclerotic Cardiovascular Disease

Jul 31, 2026 · 07:51 AM ET· updated 3h ago

Novo Nordisk today announced headline results from the ZEUS cardiovascular outcomes phase 3 trial.While ziltivekimab demonstrated target engagement and inhibition of the IL-6 pathway, as reflected by expected reductions

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Why It Matters

Novo Nordisk tested a new medicine to help heart patients, but it didn't work as well as hoped—the medicine reached its target in the body, but didn't reduce serious heart problems enough. When a medicine doesn't meet its main goal in a big test, that's important to know because it shows which treatments might not help patients the way doctors thought.

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Source: Benzinga · Read the original report at the publisher. Headline and figures shown for context; data may be delayed.

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