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Arrowhead Pharmaceuticals Announces Topline Results For Phase 3 SHASTA-3 And SHASTA-4 Clinical Studies Of Plozasiran In Patients With Severe Hypertriglyceridemia; Observes Deep, Durable, And Consistent Median Triglyceride Reductions Of 79% And 81% From Baseline

Jul 22, 2026 · 07:32 AM ET· updated 1h ago

Statistically significant reduction in acute pancreatitis events versus placebo across the entire sHTG study population, with an unprecedented 100% event reduction in high-risk patientsContinued and consistent safety

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Why It Matters

Arrowhead's medicine for high triglycerides (a type of fat in your blood) worked really well in big tests, cutting triglycerides by about 80% and preventing dangerous pancreas problems. When you hear a company's medicine passes big tests like this, it's a sign the company's future might be stronger—but real approval and success still take more steps.

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Source: Benzinga · Read the original report at the publisher. Headline and figures shown for context; data may be delayed.

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