Agios Pharma Announces Topline Results From Phase 2 Trial Of Tebapivat, Oral Pyruvate Kinase Activator, In Patients Aged 16 Years Or Older With Sickle Cell Disease
Hemoglobin response rates for tebapivat, a PK activator, were consistent with the class of medicine, but Phase 2 results did not establish a differentiated profile to support continued development in sickle cell
Agios tested a new medicine for sickle cell disease, and it worked okay—but not better than similar medicines already being made. When a company's new medicine doesn't show it's special, they have to decide if it's worth spending more money to keep going.
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